Detailed Agenda

Prophylactic & Therapeutic Intervention in Host-Pathogen Interaction

Friday June 5th – Mon 8th 2009, LO-Skolen, Helsingør, Denmark

Friday June 5th
14:30 - 14:50

Welcome:
Nils Strandberg Pedersen, Executive
Director C.E.O. Statens Serum Institut

Introductory remarks:
Prof. Peter Andersen, Statens Serum Institut

14:50 – 18:05

Regulation of the Immune Response
Chairman: Prof. FY Liew

F Nimmerjahn (Erlangen) The pro- and anti-inflammatory activities of IgG abstract

R Seder (Washington) Influence of Innate Immunity on Generating Poly-Functional T Cells abstract

Coffee / Tea

F Sallusto (Bellinzona) T lymphocyte trafficking in immunity and autoimmunity abstract

FY Liew (Glasgow) Novel Cytokines in Inflammatory Disease abstract

AF Ochsenbein (Bern) The dual role of CD27 signalling in viral infections abstract

18:15 – 20:00 Dinner
20:00 – 21:30 Poster sessions

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Saturday June 6th
08:50 – 12:10

Adjuvants/ Pathogen Pattern Receptors
Chairman: Prof. Clifford Harding

M Lotze (Pittsburg) Damage-associated molecular pattern molecules [DAMPs], Autophagy, and Redox Regulate Immunity abstract

E Raz (San Diego) Cholera toxin: Mechanisms of mucosal adjuvanticity abstract

C Harding (Cleveland) Regulation of APCs by TLR2 and Mycobacterium tuberculosis abstract

Coffee/Tea

J Brewer (Glasgow) Illuminating alum: Cellular studies of adjuvant induced responses abstract

EM Agger (Copenhagen) Novel-generation adjuvants for TB vaccine based on the effective combination of delivery systems and TLR- and NON-TLR immunomodulators abstract

12:15 Lunch
13:30 – 16:55

Regulatory cells
Chairman: Robert A. Seder

SM Behar (Harvard) CD8+ T cell effector function during pulmonary tuberculosis abstract

EJ Wherry (Philadelphia) Coregulation of CD8+ T cell exhaustion during chronic viral infection by multiple inhibitory receptors abstract

MH Andersen (Copenhagen) Protective genes as T-cell antigens abstract

Coffee/Tea

A Akbar (London) Decreased TNF-α synthesis by macrophages restricts cutaneous memory T cell immunosurveillance ageing abstract

Y Belkaid (Washington) Regulatory T cells and infection

17:15 Bus to Statens Serum Institut – Reception building 33
19:30 Dinner - Restaurant Spiseloppen

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Sunday June 7th
09:350 – 12:45

Host-Pathogen Interaction in Chronic Disease
Chairman: Dr. David Woodland

M Maini (London) Host immune response to HBV: control versus pathogenicity abstract

P Andersen (Copenhagen) Subdominant epitopes in TB abstract

Coffee/Tea

R Wyatt (Washington) HIV-1 Envelope Glycoprotein Structure and Immunogenicity abstract

A Hislop (Birmingham) The Epstein-Barr Virus-Host Interac-tion … so many experiments and still so much to learn!! abstract

D Woodland (New York) T cell memory in the lung abstract

12:45 Lunch
14:00 – 17:30

Therapeutic Vaccination/Immunotherapy
Chairman: Prof. Peter Andersen

J Dietrich (Copenhagen) Pre and post-exposure vaccines for TB abstract

G Gaudernack (Olso) Long term memory against peptide oncogene mutations following therapeutic vaccination of cancer patients abstract

Coffee/Tea

T Schmuacher (Amsterdam) MHC-based dissection of antigenb-specfic T cell immunity abstract

A Fomsgaard (Copenhagen) Therapeutic vaccines targeting subdominant CTL epitopes in HIV abstract

A K. Sewell (Cardiff) Enhanced T cell receptors for therapeutic interventions abstract

18:00 Dinner
20:00 – 21:30 Poster Sessions

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Monday June 8th
08:50 – 12:10

Prophylactic Vaccination
Chairman: Prof. Allan Randrup Thomsen

KP Karunakaran (Vancover) The Search for a Molecular T Cell Vaccine for Chlamydia abstract

L Hviid (Copenhagen) Malaria pathogenesis and immunity: the role of variant parasite antigens on the infected erythrocyte surface abstract

Coffee/Tea

PAH Moss (Birmingham) Adoptive transfer of CMV T cells, in transplantation abstract

JP Christensen (Copenhagen) Improved immunogenicity of adenoviral vaccines: Impact of tethering the vaccine antigen to MHC-class II associ-ated invariant chain abstract

PL Nara (Baltimore) Deceptive Imprinting and its role in Understanding Class II Pathogens-host interactions abstract

12:15 Lunch
13:00 -16:25

Priming/Cross-priming
Chairman: Prof. Kenneth Rock

O Bakke (Oslo) Dramatic alterations of the endosomal pathway af-ter Salmonella- invasion in epithelial cells abstract

A Oxenius (Zurich) The role of helper CD4+ T cells for primary and secondary CD8+ T cell responses abstract

AR Thomsen (Copenhagen) The Janus face of costimulation during viral infection abstract

Coffee/Tea

K Rock (Worcester) Antigen presentation and immune surveillance abstract

JW Yewdell (Bethesda) Immunodominance: It Just Ain’t What it Used to Be abstract

16:25 Meeting close

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